Animal Models of Injury and Disease
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In the Lab The Wu lab specializes in Traumatic Brain Injury (TBI), offering a unique window into understanding these puzzles. At the forefront of multidisciplinary research, the team investigates brain injury mechanisms from an integrative perspective. Employing computational models, preclinical tools, and neuroimaging, Wu uncovers insights into individual brain phenotypes, recovery processes, and personalized diagnostics.…
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In the Lab The Kaiser lab specializes in investigating sex differences in the pathophysiology of stroke, traumatic brain injury, and vascular cognitive impairment. Within the lab, the Kaiser team employs clinically relevant assessments, including magnetic resonance imaging, to evaluate tissue-level changes. Additionally, they utilize gait and neurobehavioral tests to assess functional-level outcomes in response to…
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In the Lab The Kanthasamy lab focus is on understanding the molecular mechanisms by which PKCδ regulates the apoptotic cell signaling cascade following exposure to dopaminergic neurotoxicants. They discovered that mitochondria-mediated oxidative stress signaling events in conjunction with the caspase-3-mediated cell death signaling cascade contribute to the demise of dopaminergic neuronal cells via the activation…
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In the Lab Enhancers, one type of non-coding DNA regulatory element facilitating proper spatiotemporal gene expression, are fundamental to our understanding of development and disease. Majority of genetic variants, including single-nucleotide variants (SNVs) and copy number variants (CNVs) associated with disease traits, reside in/cover enhancers. It is imperative to improve our basic understanding of enhancer…
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In the Lab Reproductive challenges in both human and livestock populations are of significant concern and are often a direct result of abnormal germ cell (oocyte and sperm) development. Aberrant germ cell development significantly affects human fertility, is the leading cause of early pregnancy loss and results in birth defects such as Down’s syndrome and…
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In the Lab The Barany lab seeks to understand the behavioral and neural mechanisms of goal-directed movement. They combine behavioral, neuroimaging, and neurostimulation methods to investigate how brain flexibly transforms goals into motor-specific representations to guide action. The long-term goal of the Barany research team is to establish a mechanistic framework rooted in basic human…
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Stice Bio Dr. Steve Stice is a University of Georgia, DW Brooks Distinguished Professor and Director of the Regenerative Bioscience Center, who holds a Georgia Research Alliance Eminent Scholar endowed chair, and is CSO of Aruna Biomedical Inc. He has over 35 years of research and development experience in biotechnology and is a co-founder of…
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In the Lab After injury, an organism must mount a series of responses to minimize and — if possible — repair damage. Some organisms regenerate poorly, while others (including humans) regenerate to differing degrees depending on the tissue that is damaged. Rarely, organisms possess the ability to repair or regenerate any missing tissue. Organisms with…
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In the Lab The goal of Cai lab is to interrogate the molecular mechanisms in facilitation of tumor progression and provide the scientific rationale for cancer treatment. Numerous oncogenic proteins require fatty acyl modifications to carry out their functions in cancer cells. Protein acylation, including myristoylation and palmitoylation, is particularly essential for leading these proteins…
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In the Lab Research in the Peroni laboratory focuses on the use of regenerative therapies ranging from cellular to blood derived products to treat musculoskeletal injuries, with a concentration on minimally invasive surgery such as laparoscopy, thoracoscopy and arthroscopy. Current research project: The surgery, performed in May, is the second successful feline kidney transplant using…