Brain Injury
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In the Lab The Wu lab specializes in Traumatic Brain Injury (TBI), offering a unique window into understanding these puzzles. At the forefront of multidisciplinary research, the team investigates brain injury mechanisms from an integrative perspective. Employing computational models, preclinical tools, and neuroimaging, Wu uncovers insights into individual brain phenotypes, recovery processes, and personalized diagnostics.…
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In the Lab The Kaiser lab specializes in investigating sex differences in the pathophysiology of stroke, traumatic brain injury, and vascular cognitive impairment. Within the lab, the Kaiser team employs clinically relevant assessments, including magnetic resonance imaging, to evaluate tissue-level changes. Additionally, they utilize gait and neurobehavioral tests to assess functional-level outcomes in response to…
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In the Lab The Samanta lab studies regeneration of myelin from neural stem cells residing in the adult mammalian brain. Myelin is the insulating sheath formed by spiral wrapping of oligodendrocyte processes around axons of neurons and its main function is to increase the nerve conduction velocity. Loss of myelin or demyelination occurs during healthy…
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In the Lab The Kanthasamy lab focus is on understanding the molecular mechanisms by which PKCδ regulates the apoptotic cell signaling cascade following exposure to dopaminergic neurotoxicants. They discovered that mitochondria-mediated oxidative stress signaling events in conjunction with the caspase-3-mediated cell death signaling cascade contribute to the demise of dopaminergic neuronal cells via the activation…
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In the Lab Kinder’s research focus is in the area of regenerative bioscience with an emphasis in stem cell therapies for traumatic brain injury (TBI) and stroke. TBI and stroke are leading causes of death and disability in the United States. However, there are currently no Food and Drug Administration (FDA)-approved therapies that promote healing…
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In the Lab The long-term research goal of the Funato lab is to develop new therapies and early detection methods for glioblastoma, one of the most lethal tumor types in both adults and children. The Funato lab utilizes cutting-edge technologies in both the oncology and stem cell fields to dissect the cellular and molecular mechanisms…
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In the Lab The Zhao group is focused on innovating novel approaches to improve magnetic resonance (MR) imaging physics at cellular level for early detection and therapeutic treatment of cancers, for tracking of stem cells, and for other biophysical and biomedical applications. MRI-based cell tracking using super-paramagnetic iron oxide (SPIO) particles provide an excellent means…
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In the Lab The Anantharam lab research focuses on neurodegenerative diseases and neurotoxicology, specifically, mitochondrial dysfunction, oxidative stress, protein aggregation, neuroinflammation and apoptosis in neurotoxicity models of Parkinson’s and prion diseases. Dr. Anantharam’s primary focus is translational research, and has extensive experience with the science of developing neuroprotective drugs and testing their efficacy in both…
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In the Lab The Xie lab is interested in engineering nanoparticles, either nanocrystal-, polymer- or protein-based, for imaging and drug delivery, with a focus on cancer. These involve developing novel materials with unique physical and chemical properties. Moreover, the lab device surface coatings of nanoparticles to impart functionalities and tailor the particles’ roles as imaging/therapy…
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In the Lab Reproductive challenges in both human and livestock populations are of significant concern and are often a direct result of abnormal germ cell (oocyte and sperm) development. Aberrant germ cell development significantly affects human fertility, is the leading cause of early pregnancy loss and results in birth defects such as Down’s syndrome and…