Diabetes
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In the Lab Interleukin-1 beta (IL-1ß) is a cytokine that is produced by the immune system and a variety of cells in response to an insult. Previous work in our lab has demonstrated that this cytokine is capable of affecting specific neurotransmitter systems in specific parts of the brain by crossing the blood brain barrier…
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Bio Dr. P. S. MohanKumar was born in Tamil Nadu, India. He received his veterinary degree from the Madras Veterinary College, Chennai, India. He went onto pursue a PhD degree in neuroendocrinology at Kansas State University following it with a stint of postdoctoral fellowship at University of Kansas Medical Center. After a brief period as…
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In the Lab Functional heterogeneity is a significant barrier to the clinical translation of many cellular therapies, including mesenchymal stromal cells (MSCs). Though MSCs have shown promise in treatment of immune diseases, the mechanisms of action and critical quality attributes (CQAs, predictors of function) in different therapeutic settings are largely unknown. The overall goal of the…
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In the Lab One of the major challenges in neurobiology is understanding the cellular and molecular mechanisms underlying development of the vertebrate central nervous system (CNS). Research in our laboratory seeks to elucidate these mechanisms by studying development of the vertebrate forebrain and visual system. We study these systems by taking advantage of mutations that…