RBC Members
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In the Lab Chromatin configuration in the nucleus or germinal vesicle (GV) of mammalian oocytes undergoes dynamic epigenetic modifications during oocyte growth. A crucial developmental transition at the culmination of oogenesis, large-scale chromatin remodeling in the GV is essential to confer the female gamete with meiotic and developmental potential. Using several models for the experimental…
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In the Lab Throughout its lifetime, adult skeletal muscle will undergo several bouts of damage and repair. However, adult skeletal muscle, which is terminally differentiated, has access to a pool of stem cells, also called satellite cells,that facilitate muscle recovery after injury. Work in our lab is directed toward discovering the critical mechanisms of muscle…