RBC Members
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B.S., University of Florida Ph.D., University of Florida In the Lab Efforts to develop stroke treatments have met with limited success despite an intense need to produce novel treatments. The failed translation of many of these therapies in clinical trials has lead to a close examination of the therapeutic development process. One of the major…
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In the Lab Chromatin configuration in the nucleus or germinal vesicle (GV) of mammalian oocytes undergoes dynamic epigenetic modifications during oocyte growth. A crucial developmental transition at the culmination of oogenesis, large-scale chromatin remodeling in the GV is essential to confer the female gamete with meiotic and developmental potential. Using several models for the experimental…
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In the Lab Throughout its lifetime, adult skeletal muscle will undergo several bouts of damage and repair. However, adult skeletal muscle, which is terminally differentiated, has access to a pool of stem cells, also called satellite cells,that facilitate muscle recovery after injury. Work in our lab is directed toward discovering the critical mechanisms of muscle…