Musculoskeletal Diseases
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In the Lab The Choo Lab studies the pathology of skeletal muscle in the context of muscular dystrophy, aging, environmental toxins, and metabolic stress using both animal models and human in vitro systems. Our research focuses on muscle stem cells and mesenchymal progenitors within skeletal muscle, investigating how these cell populations respond to diverse pathophysiological…
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Stice Bio Dr. Steve Stice is a University of Georgia, DW Brooks Distinguished Professor and Director of the Regenerative Bioscience Center, who holds a Georgia Research Alliance Eminent Scholar endowed chair, and is CSO of Aruna Biomedical Inc. He has over 35 years of research and development experience in biotechnology and is a co-founder of…
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In the Lab Research in the Peroni laboratory focuses on the use of regenerative therapies ranging from cellular to blood derived products to treat musculoskeletal injuries, with a concentration on minimally invasive surgery such as laparoscopy, thoracoscopy and arthroscopy. Research project: Working with a sheep model, collaborators from Georgia Tech and the members of the…
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In the Lab The Mortensen Lab is interested in using engineering approaches to solve important biological problems where canonical techniques and methods of thinking have failed. This requires a multidisciplinary mindset to draw together microscopy, engineering, systems level biology, and regenerative medicine. Specifically, our research uses multiphoton microscopy to enable the design of next generation…
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In the Lab Functional heterogeneity is a significant barrier to the clinical translation of many cellular therapies, including mesenchymal stromal cells (MSCs). Though MSCs have shown promise in treatment of immune diseases, the mechanisms of action and critical quality attributes (CQAs, predictors of function) in different therapeutic settings are largely unknown. The overall goal of the…
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Post-doctoral fellow University of California Los Angeles, 2010 PhD Pennsylvania State University, 2002 M.S. Pennsylvania State University, 1998 B.S. Konkuk University, 1992 In the Lab Mesenchymal Stem Cells (MSCs) are powerful multipotent progenitor cells that are present in many tissues, such as blood, bone, adipose tissue, muscle, and cartilage. MSCs exist during embryonic development and…
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In the Lab Throughout its lifetime, adult skeletal muscle will undergo several bouts of damage and repair. However, adult skeletal muscle, which is terminally differentiated, has access to a pool of stem cells, also called satellite cells,that facilitate muscle recovery after injury. Work in our lab is directed toward discovering the critical mechanisms of muscle…