Parkinson’s Disease
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In the Lab The Kanthasamy lab focus is on understanding the molecular mechanisms by which PKCδ regulates the apoptotic cell signaling cascade following exposure to dopaminergic neurotoxicants. They discovered that mitochondria-mediated oxidative stress signaling events in conjunction with the caspase-3-mediated cell death signaling cascade contribute to the demise of dopaminergic neuronal cells via the activation…
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In the Lab The Zhao group is focused on innovating novel approaches to improve magnetic resonance (MR) imaging physics at cellular level for early detection and therapeutic treatment of cancers, for tracking of stem cells, and for other biophysical and biomedical applications. MRI-based cell tracking using super-paramagnetic iron oxide (SPIO) particles provide an excellent means…
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Stice Bio Dr. Steve Stice is a University of Georgia, DW Brooks Distinguished Professor and Director of the Regenerative Bioscience Center, who holds a Georgia Research Alliance Eminent Scholar endowed chair, and is CSO of Aruna Biomedical Inc. He has over 35 years of research and development experience in biotechnology and is a co-founder of…
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In the Lab Dr. Kanthasamy’s research program has been at the forefront in unraveling the cell signaling mechanisms underlying key pathophysiological processes of PD, including mitochondrial dysfunction, oxidative stress, dopaminergic therapy, aSyn protein aggregation, gut microbiota dysbiosis, exosome trafficking, neuroinflammation, and apoptosis. Furthermore he and his team recently adopted a highly sensitive RT-QuIC assay to…
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Post-doctoral fellow University of Texas Southwestern Medical Center 2008 Ph.D. University of North Texas Health Science Center 2005 B.S / M.S. Kyungpook National University 1999 In the Lab Lee’s research focuses on understanding how inflammation influences neurodegenerative diseases. Chronic inflammation in the CNS has been strongly implicated in the pathophysiology of many neurodegenerative diseases. Microglia…