Aging
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In the Lab The Shpargel laboratory uses genetic and genomic approaches to investigate developmental disorders caused by defects in chromatin regulation. By leveraging genome-wide analyses, they are generating new hypotheses about how chromatin-modifying enzymes contribute to human disease. Their long-term goal is to translate these discoveries into therapeutic strategies that improve patient outcomes. Research Interest…
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In the Lab The Choo Lab studies the pathology of skeletal muscle in the context of muscular dystrophy, aging, environmental toxins, and metabolic stress using both animal models and human in vitro systems. Our research focuses on muscle stem cells and mesenchymal progenitors within skeletal muscle, investigating how these cell populations respond to diverse pathophysiological…
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In the Lab Kenan Song’s research, relevant to biomedical applications, leverages advanced manufacturing techniques like 3D printing to develop innovative solutions for the healthcare industry. Specifically, his work in creating microfluidic devices, porous Pelvic Organ Prolapse scaffolds, and artificial artery vessels caters to critical needs in cardiovascular and regenerative medicine. Through 3D printing, he can…
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In the Lab The Samanta lab studies regeneration of myelin from neural stem cells residing in the adult mammalian brain. Myelin is the insulating sheath formed by spiral wrapping of oligodendrocyte processes around axons of neurons and its main function is to increase the nerve conduction velocity. Loss of myelin or demyelination occurs during healthy…
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In the Lab The Zhao group is focused on innovating novel approaches to improve magnetic resonance (MR) imaging physics at cellular level for early detection and therapeutic treatment of cancers, for tracking of stem cells, and for other biophysical and biomedical applications. MRI-based cell tracking using super-paramagnetic iron oxide (SPIO) particles provide an excellent means…
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In the Lab Research in my laboratory focuses on mammalian germ cell and early embryonic development, with a major emphasis on the regulation of meiotic division in oocytes. Gametes (oocytes and sperm) have the incomparable task of transmitting the genome to successive generations. Therefore, ensuring that chromosome segregation occurs with high fidelity during meiosis is…
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In the Lab According to the CDC, chronic diseases such as cardiovascular disease and cancer account for seven of the 10 leading causes of death in the U.S. Advanced age is a common and significant risk factor for chronic diseases, and as the population rapidly ages in the coming decades, the prevalence of those diseases…
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Bio Dr. P. S. MohanKumar was born in Tamil Nadu, India. He received his veterinary degree from the Madras Veterinary College, Chennai, India. He went onto pursue a PhD degree in neuroendocrinology at Kansas State University following it with a stint of postdoctoral fellowship at University of Kansas Medical Center. After a brief period as…
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Post-doctoral fellow University of Texas Southwestern Medical Center 2008 Ph.D. University of North Texas Health Science Center 2005 B.S / M.S. Kyungpook National University 1999 In the Lab Lee’s research focuses on understanding how inflammation influences neurodegenerative diseases. Chronic inflammation in the CNS has been strongly implicated in the pathophysiology of many neurodegenerative diseases. Microglia…
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In the Lab One of the major challenges in neurobiology is understanding the cellular and molecular mechanisms underlying development of the vertebrate central nervous system (CNS). Research in our laboratory seeks to elucidate these mechanisms by studying development of the vertebrate forebrain and visual system. We study these systems by taking advantage of mutations that…